Calendar In the past decade, the emergence of chimeric antigen receptor (CAR) T-cell therapy has led to a cellular immunotherapy revolution against various cancers.Although CAR-T cell therapies have demonstrated remarkable efficacy for patients with certain B cell driven hematological malignancies, further studies are required to broaden the use of
The proliferative pool of neural progenitor cells is maintained by exquisitely controlled mechanisms for cell cycle regulation.The Na-K-Cl cotransporter NKCC1 is important for regulating cell volume and the proliferation of different cell types in vitro.NKCC1 is expressed in ventral telencephalon of embryonic brains suggesting a potential role in n
Autism spectrum disorders (ASDs) are perhaps the most severe, intractable and challenging child psychiatric disorders.They are complex, pervasive and highly heterogeneous and depend on multifactorial neurodevelopmental conditions.Although the pathogenesis of autism remains unclear, it revolves around altered neurodevelopmental patterns and their im
Selective chemical reactions of biomolecules are some of the important tools for investigations by biological studies.We have developed the selective crosslinking reactions to form covalent bonds to DNA or RNA using crosslinking oligonucleotides (CFO) bearing reactive bases.In this study, we designed the cross-linkable Boys S/S Shirt 4-amino-6-oxo-